- Sand Gravel & Aggregate, Clarkesville
- Sandwich Shop Restaurants, Clarkesville
- Satellite Descrambling & Programming Service, Clarkesville
- Satellite TV Service, Clarkesville
- Sawdust & Shavings, Clarkesville
- Sawmill & Planing Mills, Clarkesville
- Sawmill Supplies & Equipment Repair, Clarkesville
- Scrap & Waste Materials, Clarkesville
- Secondary Schools, Clarkesville
- Security & Surveillance System & Equipment, Clarkesville
- Security Alarm Systems - Home & Business, Clarkesville
- Security Brokers & Dealers, Clarkesville
- Security Control Systems & Monitoring, Clarkesville - Polygraph, Lie Detector, CCTV, Fire Sensor Equipment, Etc
- Security Services, Clarkesville
- Septic Tank Installation & Repair, Clarkesville - Septic Systems
- Septic Tank Pumping & Cleaning, Clarkesville - Septic Systems
- Septic Tanks & Septic Systems Contractors, Clarkesville - Installation, Repair, Service, Cleaning & Pumping Septic Tanks
- Sewing & Yarn Stores & Supplies, Clarkesville
- Sewing Machine Repair & Service, Clarkesville
- Shopping & Shopping Services, Clarkesville
- Signs, Clarkesville
- Skin Care & Cosmetology Salons, Clarkesville
- Skin Care Products & Treatments, Clarkesville
- Skylights, Clarkesville - Skylight Shades, Blinds, Covers & More
- Small Engine Parts Wholesale, Clarkesville
- Social Security And Disability Attorneys & Lawyers, Clarkesville
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- Social Security And Disability Lawyers & Attorneys, Clarkesville
- Social Services & Welfare, Clarkesville
- Societies & Foundation Associations, Clarkesville
- Sod & Sodding Service, Clarkesville
- Solariums & Garden Rooms, Clarkesville
- Special Interest Schools Or Instruction, Clarkesville
- Specialty Animal Services, Clarkesville
- Specialty Goods Storage, Clarkesville
- Specialty Stores, Clarkesville
- Specialty Vehicle Rental & Leasing, Clarkesville
- Speech & Hearing Specialists, Clarkesville
- Speech Pathologists, Clarkesville - Speech & Language Therapy
- Sporting Goods Equipment Rental, Clarkesville
- Sporting Goods Stores, Clarkesville
- Sports & Recreational Services, Clarkesville
- Staffing & Support Services, Clarkesville
- Stairs & Railings Contractors, Clarkesville - Metal & Wood Stairs, Spiral Staircase & Stair Railing - Installation & Repair
- Stairs, Balcony, Terrace & Steeple Contractors, Clarkesville
- State Government, Clarkesville
- State Parks, Clarkesville
- Steak House Restaurants, Clarkesville
- Steel Manufacturers, Clarkesville
- Stucco Siding Contractors, Clarkesville - Stucco Repair & Installation
- Stucco Siding, Granite & Grouting Contractors, Clarkesville
- Surplus & Salvage Merchandise, Clarkesville
- Surveyor Services, Clarkesville - Surveying Service
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